Bought the full 5150 rules and played the first game over the weekend. We were both really confused as you'd expect for the first game ... especially as it's so different from other games we've played. I think we played many parts of the rules wrong and we also started out with space marines who were really too elite for an intro game. The space marines ended up passing almost every reaction test they needed so we didn't get a great feel for that aspect of the game.
There were definitely elements that I liked and as I started reading the rules again, I realized we did a lot of stuff wrong. Still, it's definitely an interesting game and I suspect the next game will work out better.